111年第二次藥物治療學解析67

67.25歲男性有脂漏性皮膚炎,病灶主要在耳部、髮際、鼻唇溝及前額,下列治療何者最適當?

A.diflorasone diacetate 0.05% ointment,使用>7日

B.diflorasone diacetate 0.05% ointment,使用<7日

C.hydrocortisone valerate 0.2% cream,使用>7日

D.hydrocortisone valerate 0.2% cream,使用<7日

答: D

Especially in thin-skinned areas such as the face, fluorinated corticosteroids are more likely to cause these localized reactions because of their increased-potency than nonfluorinated corticosteroids. Therefore, whenever possible only nonfluorinated topical corticosteroids should be used in thin-skinned areas for the shortest possible time. Because the use of corticosteroids is expected to last less than a week, the risk of developing local complications is minimal with a nonfluorinated product.

Because the lesions are on the face, a nonfluorinated corticosteroid such as

hydrocortisone valerate or mometasone should be used to minimize the potential for

adverse effects in this thin-skinned area.

由於病變位於面部(耳部、髮際、鼻唇溝及前額),因此應使用nonfluorinated corticosteroid,例如hydrocortisone valerate or mometasone,以盡量減少對該薄皮膚區域產生不利影響的可能性。

故(D)為最佳解答

參照Applied Therapeutics: The Clinical Use of Drugs (11 Edition) P816

 

 

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